The four-volume set LNCS 15364-15367 constitutes the refereed proceedings of the 22nd International Conference on Theory of Cryptography, TCC 2024, held in Milan, Italy, in December 2024. The total of 68 full papers presented in the proceedings was carefully reviewed and selected from 172 submissions. They focus on topics such as: proofs; math and foundations; consensus and messaging; quantum; kolmogorov and OWFs; encryption; quantum and black-box separations; authentication and sequentiality; obfuscation and homomorphism; multi-party computation; information-theoretic cryptography; and secret sharing.