This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address preclinical animal models for cardiac research and clinical trials performed, cardiac mapping systems, heart-valve therapies and other device-based tools and technologies for cardiac diagnoses and treatments. Once again, companion of supplementary videos offer unique insights into the device-tissue interfaces, including those within beating hearts: i.e., these supplemental videos enhance ones understandings of key points within the text. The "Handbook of Cardiac Anatomy, Physiology and Devices", the Fourth Edition is a comprehensive and state-of-the art resource textbook that should provide clinicians and biomedical engineers alike, with the authoritative information and background they need to work on and implement tomorrow's generation of life-saving cardiac therapies and devices.