The two-volume proceedings set CCIS 2299 and 2300, constitutes the refereed proceedings of the 43rd IBIMA Conference on Artificial intelligence and Machine Learning, IBIMA-AI 2024, held in Madrid, Spain, in June 26-27, 2024. The 44 full papers and 18 short papers included in this book were carefully reviewed and selected from 119 submissions. They were organized in topical sections as follows: Part I: Artificial Intelligence and Machine Learning; Information Systems and Communications Technologies. Part II: Artificial Intelligence and Machine Learning ; Software Engineering; Computer Security and Privacy.