This book provides a comprehensive overview of the cutting-edge research in the bioengineering of halophytes, with a particular focus on advancements in biotechnology, transcriptomics, proteomics, metabolomics, and genomics. Halophytes are a unique group of plants that have adapted to grow in extreme environmental conditions such as high salt, low water, and high temperatures. In desert conditions, these plants are crucial for supporting animal and human life. However, overexploitation of these plants degrades the ecosystem. Sustainable utilization and improvement of these plants through modern tools are essential for the sustainability of both the plants and the environment. Halophytes possess unique metabolic and physiological features, making them an attractive target for bioengineering. Recent advancements in bioengineering have significantly enhanced the study and manipulation of halophytes. By exploring the intricacies of these technologies, this book addresses key questions and challenges in harnessing the potential of halophytes for sustainable plant resources, environmental remediation, and novel biotechnological applications. This book will be valuable for researchers in plant biology, environmental studies, desertification, plant improvement, and biotechnology.