The book provides a comprehensive exploration of sustainable practices in biomaterial development for biomedical applications, covering diverse topics such as green synthesis methods, the potential of biodegradable materials, renewable resources for biopolymers, strategies in polymer synthesis, bio-mediated nanomaterials, sustainable manufacturing techniques including 3D and 4D printing, protein-based biomaterials, composite biomaterials derived from cellulose, chitin, and chitosan, as well as hydroxyapatite-starch-based biomaterials, carbonaceous materials, eco-friendly synthesis of metal and metal oxide nanomaterials, silk fibroin scaffold synthesis, utilization of green catalysts, cellulose-derived hydrogels for tissue engineering, plant extract-mediated synthesis of metallic nanoparticles, and eggshell-derived biomaterial synthesis. This multifaceted approach addresses the pressing need for environmentally conscious solutions in the field of biomedical engineering, offering insights into the synthesis, properties, and applications of sustainable biomaterials. This book provides a comprehensive understanding of biodegradable materials, offering a valuable asset for researchers and Ph.D. scholars involved in the ever-changing field of sustainable biomedical engineering.