This book constitutes the refereed proceedings of the 15th International Conference on Software Business, ICSOB 2024, which took place in Utrecht, The Netherlands, during November 18-20, 2024. The special theme of ICSOB 2024 was Ethics, Equity, and Sustainability in Software Business. The 23 full papers and 13 short papers presented in this book were carefully reviewed and selected from 98 submissions. The papers are organized in the following topical sections: Ethical Challenges in Software Development; Developer Experience and Ecosystem Trust; Transparency and Trust in AI; Diversity and Inclusion in Software Business; Sustainable ICT; Experimentation and Innovations; Tools in Software Ecosystems; and Software Startups and Digital Transformation.