This book constitutes the refereed proceedings of the 25th International Conference on Parallel and Distributed Computing, Applications and Technologies, PDCAT 2024, held in Hong Kong, China, during December 14-16, 2024. The 47 full papers and 8 short papers included in this book were carefully reviewed and selected from 114 submissions. They focus on advances in parallel and distributed computing, including parallel architectures, algorithms, and programming techniques.