This book provides concise and practical information on clinical management of different kinds of refractory wounds in a case-based format, including diabetic foot ulcer wounds, surgical trauma wounds, lower extremity ischemic disease wounds, neuropathy wounds, and pressure ulcer wounds, etc. Following the similar format, each chapter covers typical and/or challenging case, starting from medical history and physical examination, to diagnosis, clinical management, and in-depth analysis of key points in treatment. It will be a helpful reference for practitioners working in management of various refractory wounds. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content, so that the book will read stylistically different from a conventional translation.