Diseases affecting the orbit and oculofacial region present with a diverse range of clinical manifestations. Space-occupying lesions within the orbit can arise from infections, inflammations, vascular malformations, or malignancies. This variability in presentation is largely attributed to the complex anatomy of the orbit and the diverse nature of the disease processes that often appear as orbital inflammatory disorders. This book provides an in-depth exploration of orbital inflammatory disorders, focusing on their diagnosis and management. It includes chapters on cutting-edge topics such as tear proteomics, orbital and facial ultrasonography, AI-assisted point-of-care ultrasonography, imaging bioinformatics, and precision medicine.