This book presents the scientific as well as industrial perspectives, challenges, and advances in minimally invasive drug delivery systems for topical applications. It also covers the regulatory requirements and specifically discusses all the intellectual property rights filed and granted throughout the globe for minimally invasive systems. This book presents detailed analyses of various minimally invasive drug delivery methods as well as the recent advances in devices such as microneedles, iontophoretic devices, probes, etc. This book will be of keen interest to a wide range of audiences, including clinical researchers working in the field of drug delivery and disease diagnosis, as well as undergraduate and postgraduate students from various disciplines such as pharmacy, pharmacology, pharmaceutics, biotechnology, and health sciences.