Cardiac surgery is a highly complex and ever-evolving field, with cardiopulmonary bypass (CPB) playing a crucial role in modern surgical practice. For trainees rotating in the cardiac surgery room, gaining both scientific and practical knowledge of clinical perfusion can be challenging without a comprehensive and accessible reference. This book addresses that need by providing a clear, focused, and concise guide to the principles and management of clinical perfusion, incorporating the latest advancements in the field. Designed for trainees, junior cardiac anesthesiologists, cardiac surgeons, and perfusionists, it lays the essential foundation for mastering perfusion techniques and ensuring success in this critical aspect of cardiac surgery.