This book, now in an extensively revised second edition, describes the latest developments in planning, materials, provides the practitioner with a framework for establishing a diagnosis and developing a suitable treatment plan in patients presenting with a range of developmental defects of the teeth and the craniofacial complex. The conditions covered include failure of tooth eruption, hypodontia, premature tooth exfoliation, defects of enamel development, and defects of dentin development, with full consideration of both syndromic and non-syndromic defects, including facial clefting. In each case the phenotype and genotype are first described, followed by diagnostic information, including the availability of genetic testing, and treatment options. Summarizing tables highlight the key diagnostic features, and helpful illustrated case presentations are included. Cleft palate is addressed, with details on etiology, phenotypes, treatment timing and approaches, and dental management. The closing chapter provides stimulating reflections on potential future directions in the diagnosis and treatment of these disorders.