This book describes many types of Conference matrices and shows the case studies of application. Also, this book deals with putting the operation procedure and data analysis for optimizing. After reading this book, many researchers in universities or industries directly can apply various methods in this book to researching subjects, the trial numbers, and cost. And it saves time around 1/3-1/2 in total research activities. Especially, this book contributes SDGs and saving GLOBAL warming which need to countermeasures as well.