The proposed textbook contains real-life cases of Endocrinology and Metabolism. It is written in a context-based format, highlighting the patient's presenting problems and demonstrating how to delve into these issues to reach a diagnosis and subsequent management. Students and trainees will learn the approach to evaluating and investigating cases through hands-on training. The book highlights challenging real cases and contemporary investigations, including genetic or molecular diagnoses where applicable. It promotes an active learning process, as it is designed in an MCQ format with self-solving quizzes to stimulate brainstorming within the reader. It will provoke a desire for further learning as readers engage with the discussions in each chapter. While going through this book, readers will be captivated by the unique way each case unfolds and will not feel bored as they might with a regular textbook. This book is primarily great asset for Endocrinologists and training residents/fellows in Endocrinology, but it is also uselful for physicians in other specialties, such as Internal medicine Pediatrics and Reproductive Endocrinology. .