This textbook provides a comprehensive reference on adult vaccines and immunization practices tailored to the European context. The reader is guided from assessing the health burden of vaccine-preventable infections to evaluating the cost-effectiveness of new adult vaccination schedules, introducing and establishing such initiatives, and communicating and managing vaccination programs. The authors update on routine and new vaccines for a number of common pathogens in Europe, such as SARS-CoV-2, RSV and influenza, and also provide information on travel-related vaccinations. The book discusses in detail individualized, risk-based vaccination for different patient groups and also provides insights into current pipeline development, and an outlook on the future prospects for adult vaccination. All editors are part of the Adult Immunization Board (AIB) created in November 2022. The AIB is a European platform that brings together experts to address key challenges in adult vaccination. The goal is to promote evidence-based policies, knowledge sharing, and cross-country collaboration to improve adult immunization. The AIB secretariat based at the University of Antwerp and University of Florence is responsible for the operational and scientific tasks of the AIB and took the lead in coordinating the writing of this book supported by its AIB advisors and other selected experts.