This comprehensive volume offers an in-depth exploration of dermatologic therapeutics, encompassing both foundational principles and the latest advancements in the field. Each drug is presented with a clear and concise overview, covering its introduction, mechanism of action, pharmacokinetics, indications, contraindications, clinical applications, adverse effects, and considerations for use during pregnancy, lactation, and in geriatric and pediatric populations. Designed as an essential resource for clinicians, researchers, and students, the book provides a thorough understanding of both systemic and topical therapies in dermatology. Besides, it features detailed discussions on retinoids, biological immunomodulators and immunosuppressive agents-core components of modern dermatologic treatment. Enhanced with numerous flow diagrams and tables the book effectively illustrates key concepts and therapeutic pathways, offering readers a clear and structured perspective on clinical decision-making in dermatology. This is volume 1 of the set of three volumes.