This book constitutes the proceedings of the 6th International Conference on Biomimetic and Biohybrid Systems, Living Machines 2017, held in Stanford, CA, USA, in July 2017. The 42 full and 19 short papers presented in this volume were carefully reviewed and selected from 63 submissions. The theme of the conference encompasses biomimetic methods for manufacture, repair and recycling inspired by natural processes such as reproduction, digestion, morphogenesis and metamorphosis.