This book presents 8 tutorial lectures given by leading researchers at the 16th edition of the International School on Formal Methods for the Design of Computer, Communication and Software Systems, SFM 2016, held in Bertinoro, Italy, in June 2016. SFM 2016 was devoted to the Quantitative Evaluation of Collective Adaptive Systems and covered topics such as self-organization in distributed systems, scalable quantitative analysis, spatio-temporal models, and aggregate programming.