This book constitutes revised selected papers from the 10th International Conference on Critical Information Infrastructures Security, CRITIS 2015, held in Berlin, Germany, in October 2015. The 18 full and 6 short papers presented in this volume were carefully reviewed and selected from 54 submissions. They are organized in topical sections named: critical information infrastructure protection; critical infrastructure resilience assessment; emergency management: critical infrastructure preparedness; modelling, simulation and analysis approaches; electric grid protection and resilience; and CIPRNet young CRITIS award candidate papers.