This book contains revised selected papers from the 22nd International Conference on Selected Areas in Cryptography, SAC 2015, held in Sackville, NB, Canada in August 2015. The 26 full papers and 3 short papers presented in this volume were carefully reviewed and selected from 91 submissions. They are organized in topical sections named: privacy enhancing technologies; cryptanalysis of symmetric-key primitives; implementation of cryptographic schemes; short papers; privacy preserving data processing; side channel attacks and defenses; new cryptographic constructions; authenticated encryption; on the hardness of mathematical problems; and cryptanalysis of authenticated encryption schemes.