This book constitutes the proceedings of the 16th IFIP TC8 International Conference on Computer Information Systems and Industrial Management, CISIM 2017, held in Bialystok, Poland, in June 2017. The 60 regular papers presented together with 5 keynotes were carefully reviewed and Selected from 85 submissions. They are organized in the following topical sections: algorithms; biometrics and pattern recognition applications; data analysis and information retrieval; engineering of enterprise software products; industrial management and other applications; modelling and optimization; various aspects of computer security.