This two-volume-set (LNCS 9573 and 9574) constitutes the refereed proceedings of the 11th International Conference of Parallel Processing and Applied Mathematics, PPAM 2015, held in Krakow, Poland, in September 2015. The 111 revised full papers presented in both volumes were carefully reviewed and selected from 196 submissions. The focus of PPAM 2015 was on models, algorithms, and software tools which facilitate efficient and convenient utilization of modern parallel and distributed computing architectures, as well as on large-scale applications, including big data problems.