This publication reflects the most current and exciting developments in the field of stereotactic radiosurgery today. It marks the second volume in the book series 'Radiosurgery', which is the official peer-reviewed publication of the International Stereotactic Radiosurgery Society. This latest volume includes long-term data on benign tumors, and evaluations on the role of whole-brain fractionated radiation therapy in patients with solitary metastases. Multicenter studies, methods to evaluate our data, grading scales, and novel irradiation approaches, together with technological improvements, characterize the new drive in this direction and form an important part of this book. It provides a vital source of scientific information on radiobiology, vascular malformation radiosurgery, benign and malignant brain tumor radiosurgery, extracranial radiosurgery, technological developments in radiosurgery, complication avoidance, and economic issues. This book should be read by physicians and scientists interested in neurosurgery, radiation oncology, medical physics, neuroradiology, and neurology, in order to remain current with important developments in the field and their impact on the management of brain disease.