1. Fibrosis and Heart Failure - Cause or Effect? -- 2. Fibroblast Activation in the Infarcted Myocardium -- 3. Mechanical and Matrix Regulation of Valvular Fibrosis -- 4. Bone Marrow-Derived Progenitor Cells, micro-RNA and Fibrosis -- 5. The Stressful Life of Cardiac Myofibroblasts -- 6. Pathogenic Origins of Fibrosis in the Hypertensive Heart Disease that Accompanies Aldosteronism -- 7. Embryological origin of valve progenitor cells -- 8. Diverse cellular origins of cardiac fibroblasts -- 9. Non-Canonical Regulation of TGF-β1 Signaling: A Role for Ski/Sno and YAP/TAZ -- 10. Molecular mechanisms of smooth muscle and fibroblast phenotype conversions in the failing heart -- 11. Current and future strategies for the diagnosis and treatment of cardiac fibrosis -- 12. Remodelling of the cardiac extracellular matrix:  Role of collagen degradation and accumulation in  pathogenesis of heart failure -- 13. Matrix Metalloproteinase 9 (MMP-9): The Middle-Man of Post Myocardial Infarction Extracellular Matrix Remodelling -- 14. Collagen processing and its role in Fibrosis -- 15. Mechanisms of Cardiac Fibrosis -- 16. Mathematical Simulations of Sphingosine-1-Phosphate Actions on Mammalian Ventricular Myofibroblasts and Myocytes -- 17. Extracellular Matrix and Cardiac Disease: Surgical and Scientific Perspectives -- 18. The Role of Neurohumoral Activation in Cardiac Fibrosis and Heart Failure -- 19. Natriuretic peptides: critical regulators of cardiac fibroblasts and the extracellular matrix in the heart -- 20. Cardiac Tissue Engineering for the Treatment of Heart Failure Post-Infarction -- 21. Mechanisms of Cardiac Valve Failure and the Development of Tissue Engineered Heart Valves.