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Multiparticulate oral drug delivery için kapak resmi
Başlık:
Multiparticulate oral drug delivery
Yazar:
Ghebre-Sellassie, Isaac, 1947-
ISBN:
9781482215267

9780367804541

9780824791919
Yayın Bilgileri:
New York : Informa healthcare ; Boca Raton, Fla. : CRC Press, ©1994.
Fiziksel Tanımlama:
1 online resource (viii, 480 pages) : illustrations.
Seri:
Drugs and the pharmaceutical sciences ; 65
İçerik:
1. Manufacture of core pellets by balling / Lucy S.C. Wan -- 2. Preparation of micropellets by spray congealing / A. Atilld Hincal and H. S¿heyla Ka? -- 3. Cryopelletization / Axel Knock -- 4. Coating of multiparticulates using polymeric solutions : formulation and process considerations / Klaus Lehmann -- 5. Coating of multiparticulates using polymeric dispersions : formulation and process considerations / Yoshinobu Fukumori -- 6. Coating of multiparticulates using molten materials : formulation and process considerations / David M. Jones and Phillip J. Percel -- 7. Suspensions and dispersible dosage forms of multiparticulates / Roland Bodmeier and Ornlaksana Paeratakul -- 8. Multiparticulate encapsulation equipment and process / Donald K. Lightfoot -- 9. Compaction of multiparticulate oral dosage forms / Metin Qelik -- 10. Key factors in the development of modified-release pellets / Stuart C. Porter and Isaac Ghebre-Sellassie -- 11. Mechanisms of release from coated pellets / Jennifer B. Dressman [and others] -- 12. Biopharmaceutical aspects of multiparticulates / Johannes Kramer and Henning Blume -- 13. In vivo behavior of multiparticulate versus single-unit dose formulations / George A. Digenis -- 14. Capsule shell composition and manufacturing / Ronnie Millender -- 15. Packaging of multiparticulate dosage forms : materials and equipment / K.S. Murthy, Franz Reiterer, and Jtirgen Wendt -- 16. Marketing considerations for multiparticulate drug delivery systems / Roland Daumesnil.
Özet:
This definitive reference explores the various aspects of multiparticulate dosage form development-assessing the in vivo behavior and performance of multiparticulates as well as comparing their market position to other dosage forms.Discussing-for the first time in a comprehensive manner-alternative pelletization techniques such as balling (spherical agglomeration), spray congealing, and cryopelletization, Multiparticulate Oral Drug Delivery describes formulation and processing variables that affect the formation, integrity, and performance of coatings derived from molten materials and polymeric solutions and dispersions analyzes the biopharmaceutical aspects and in vivo performance of multiparticulate drug delivery systems details the idiosyncrasies of the manufacturing process of hard-shell gelatin capsules explains the different kinds of packaging materials and machinery and the importance of packaging during the development phase and beyond previews the marketing considerations of multiparticulate systems in the years to come presents practical solutions to problems encountered in the area of film-coating processes and more!
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Arıyor...
E-Kitap 538582-1001 RS201 .N35 M856 1994
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