Introduction to mitochondria / Carolyn D. Berdanier -- Mitochondrial bioenergetics in intact tissue / Richard L. Veech -- The human mitochondrial genome: mechanisms of expression and maintenance / Jan-Willem Taanman and Sin̥ Llewellyn Williams -- Oxidative phosphorylation disease: diagnosis and pathogenesis / John M. Shoffner -- Using mitochondrial DNA in population surveys / Carolyn D. Berdanier -- Mitochondrial DNA mutation, oxidative stress, and alteration of gene expression in human aging / Hsin--Chen Lee and Yau-Huei Wei -- Mitochondrial DNA in cardiomyopathies / Nobuakira Takeda -- Mitochondria in Diabetes mellitus / Hong Kyu Lee -- Drugs, nutrients, and hormones in mitochondrial function / Carolyn D. Berdanier -- Bacterial F1F0 ATP synthase as a model for complex V / Brian D. Cain, Tammy Bohannon Grabar, and Depa Bhatt -- Cybrids in the study of animal mitochondrial genetics and pathology / Ian A. Trounce and Carl A. Pinkert -- Animal modeling: from transgenesis to transmitochondrial models / Carl A. Pinkert and Ian A. Trounce -- BHE/Cdb rats as tools to study mitochondrial gene expression / Carolyn D. Berdanier and Moon-Jeong Chang Kim -- Appendix 1 -- Appendix 2.