A trail of research on lipoic acid / Lester J. Reed -- Lipoic acid biosynthesis / Natasha M. Nesbitt ... [et al.] -- The search for potent alpha-lipoic acid derivatives: chemical and pharmacological aspects / Moriya Ben Yakir, Yehoshua Katzhendler, and Shlomo Sasson -- Novel indole lipoic acid derivatives: synthesis and their antioxidant effects / A. Selen Gurkan and Erdem Buyukbingol -- Alpha-keto acid dehydrogenase complexes and glycine cleavage system: their regulation and involvement in pathways of carbohydrate, protein, and fat metabolism / Robert A. Harris ... [et al.] -- Pyruvate dehydrogenase complex regulation and lipoic acid / Lioubov G. Korotchkina and Mulchand S. Patel -- Role of lipoyl domains in the function and regulation of the mammalian pyruvate dehydrogenase complex / Thomas E. Roche ... [et al.] --

Inactivation and inhibition of alpha-ketoglutarate dehydrogenase: oxidative modification of lipoic acid / Kenneth M. Humphries, Amy C. Nulton-Persson, and Luke I. Szweda -- Lipoate-protein ligase A: structure and function / Kazuko Fujiwara ... [et al.] -- An evaluation of the stability and pharmacokinetics of R-lipoic acid and R-dihydrolipoic acid dosage forms in human plasma from healthy subjects / David A. Carlson ... [et al.] -- Pharmacokinetics, metabolism, and renal excretion of alpha-lipoic acid and its main metabolites in humans / Jens Teichert and Rainer Preiss -- Modulation of cellular redox and metabolic status by lipoic acid / Derrick Han ... [et al.] -- Redoxin connection of lipoic acid / Jos ̌Antonio Br̀cena ... [et al.] -- Lipoic acid as an inducer of phase II detoxification enzymes through activation of Nrf2-dependent gene expression / Kate Peterson Shay, Swapna Shenvi, and Tory M. Hagen --

Deficiency disorders of components of PDH complex: E2, E3, and E3BP deficiencies / Jessie M. Cameron, Mary C. Maj, and Brian H. Robinson -- Relationship between primary biliary cirrhosis and lipoic acid / Carlo Selmi ... [et al.] -- Effects of lipoic acid on insulin action in animal models of insulin resistance / Erik J. Henriksen and Stephan Jacob -- Activation of cytoprotective signaling pathways by alpha-lipoic acid / Alexandra K. Kiemer and Britta Diesel -- Selenotrisulfide derivatives of alpha-lipoic acid: potential use as a novel topical antioxidant / William T. Self -- Alpha-lipoic acid: a potent mitochondrial nutrient for improving memory deficit, oxidative stress, and mitochondrial dysfunction / Jiankang Liu -- Effects of alpha-lipoic acid on AMP-activated protein kinase in different tissues: therapeutic implications for the metabolic syndrome / Eun Hee Koh ... [et al.].