
Başlık:
Protein Kinase CK2 Cellular Function in Normal and Disease States
Yazar:
Ahmed, Khalil. editor.
ISBN:
9783319145440
Basım Bilgisi:
1st ed. 2015.
Fiziksel Tanımlama:
XXIII, 378 p. 91 illus., 60 illus. in color. online resource.
Seri:
Advances in Biochemistry in Health and Disease, 12
İçerik:
1. CK2 Suppression of Apoptosis -- 2. Structural Determinants of CK2 Regulation -- 3. Targeting Protein Kinase: CK2 Suppresses Pro-Survival Signaling Pathways and Growth of Gliobastoma -- 4. The Roles of CK2 in Drosophila Neurogenesis -- 5. Targeting the CK2 Subunit Interface: Challenge and Usefulness -- 6. CK2 in Wnt/β-catenin signaling and embryo development -- 7. Defective expression of CK2β promotes EMT and stemness properties both required for breast cancer progression -- 8. Chemical Biology Approaches to Identify CK2 Substrates and Perform Unbiased Evaluation of CK2 Inhibitors -- 9. Development of Screening Systems and Identification of Novel Potent Inhibitors of Human Protein Kinase CK2 -- 10. Protein Kinase CK2: At the Crossroad of Regulatory Cellular Pathways -- 11. Functional Regulation of DYRK Family Protein Kinases by Cellular Binding Partners -- 12. Regulation of CK2 in pancreatic β cells -- 13. Recent impressions from the configurational and conformational space captured by protein kinase CK2 -- 14. Role of CK2 in Plant Responses to Abiotic Stress -- 15. "Genuine" Casein Kinase: The False Sister of CK2: Phosphorylates-Secreted Proteins -- 16. CK2: - A Novel Player in L-DOPA induced dyskinesia in a mouse model of Parkinson's disease -- 17. CK2 function in the regulation of Akt Pathway: new findings and perspectives -- 18. CK2 structure from yeast to human -- 19. Cellular zinc signaling is triggered by CK2 -- 20. A Nanomedicine Approach to Targeting CK2 for Cancer therapy -- 21. Bisubstrate approach for construction of high-affinity inhibitors and optical probes for protein kinase CK2.
Tüzel Kişi Ek Girişi:
Elektronik Erişim:
https://doi.org/10.1007/978-3-319-14544-0Kopya: 1