Chapter 1. Orphan lung diseases: from definition to organisation of care.-Chapter 2. The challenge of clinical research in orphan diseases -- Chapter 3. Chronic bronchiolitis in adults -- Chapter 4. Allergic bronchopulmonary mycosis -- Chapter 5. Orphan tracheopathies -- Chapter 6. Amyloidosis of the lungs and airways -- Chapter 7. Eosinophilic granulomatosis with polyangiitis -- Chapter 8. Granulomatosis with polyangiitis -- Chapter 9. Alveolar hemorrhage -- Chapter 10. Pulmonary manifestations of large vessel vasculitis (Behçet and Takayasu disease) -- Chapter 11. Hepato-pulmonary syndrome -- Chapter 12. Systemic sclerosis and the lung -- Chapter 13. Rheumatoid arthritis and the lung -- Chapter 14. Lung disease in systemic lupus erythematosus, myositis, Sjögren disease and mixed connective tissue diseases -- Chapter 15. Interstitial pneumonia with autoimmune features, and overlap interstitial pneumonia -- Chapter 16. Non-Langerhans cell histiocytosis and the lung -- Chapter 17. Idiopathic eosinophilic pneumonias -- Chapter 18. Langerhans cell granulomatosis and smoking-related interstitial lung diseases -- Chapter 19. Lymphangioleiomyomatosis -- Chapter 20. Multiple cystic lung disease -- Chapter 21. Complex Thoracic Lymphatic Disorders of Adults -- Chapter 22. Pulmonary alveolar proteinosis -- Chapter 23. Gasteroesosophageal reflux, idiopathic pulmonary fibrosis and lung transplantation -- Chapter 24. Genetic and familial pulmonary fibrosis related to monogenic diseases -- Chapter 25. Diffuse bronchiectasis of genetic or idiopathic origin -- Chapter 26. Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia -- Chapter 27. Pulmonary alveolar microlithiasis -- Chapter 28. Rare diffuse lung diseases of genetic origin -- Chapter 29. Imaging approach to interstitial lung disease -- Chapter 30. Bronchoscopic approach to interstitial lung disease -- Chapter 31. An integrated approach to diagnosing interstitial lung disease -- Chapter 32. Idiopathic Pulmonary fibrosis and the many faces of UIP -- Chapter 33. Combined pulmonary fibrosis and emphysema (syndrome) -- Chapter 34. Nonspecific interstitial pneumonia, idiopathic or secondary -- Chapter 35. Organising pneumonias and acute interstitial pneumonia -- Chapter 36. Pleuro pulmonary fibroelastosis -- Chapter 37.Interstitial lung diseases of occupational origin -- Chapter 38. Unclassifiable Interstitital Lung Disease -- Chapter 39. Lymphoproliferative lung diseases -- Chapter 40. Pulmonary manifestations of hematological malignancies and recipients of bone marrow or stem cell transplantation -- Chapter 41. Pulmonary hypertension in orphan lung diseases -- Chapter 42. Drug-induced / iatrogenic respiratory disease: With emphasis on unusual, rare and emergent drug-induced reactions -- Chapter 43. Malignant mimics of orphan lung diseases.