INTRODUCTORY CHAPTERS: Anatomy and physiology of adipose tissue -- Regulation of energy intake -- Obesity: definition and epidemiology -- METABOLISM & ENDOCRINOLOGY: Obesity and thyroid function -- Hypothalamic Growth Hormone/IGF-1 Axis -- Adrenal function and obesity -- Ovarian function and obesity: PCOS, menopause -- Obesity and osteoporosis -- Sarcopenic obesity -- Obesity and testicular function -- Obesity and Glucose metabolism -- Dyslipidemia and cardiovascular risk in obesity -- Pulmonary complications of obesity -- Sexual distress in obesity -- EVALUATION OF OBESE SUBJECTS: Clinical evaluation -- Nutritional status evaluation: energy balance and body composition -- Psychiatric and psychological evaluation -- Functional evaluation -- Impairment of quality of life in obesity -- THERAPEUTIC APPROACH: Therapeutic education and psychotherapy -- Dietary intervention and nutritional counseling -- Physical activity and training prescription -- Prescription Medications for the Treatment of Obesity -- Bariatric surgery -- Reconstructive plastic surgery -- Nutritional, metabolic and psychological rehabilitation -- Increasing adherence to diet and exercise through cognitive behavioral strategies -- Interdisciplinary approach to obesity.