1 Historical Notes -- 2 Definition, Terminology and Prevalence -- 3 Diagnostic Approach to white coat effect and white coat hypertension -- 4 Neurogenic and Non-neurogenic Mechanisms -- 5 Predictive Factors -- 6 White coat hypertension and cardiovascular morbidity and mortality -- 7 White coat hypertension and Target Organ Damage -- 8 White Coat Hypertension, metabolic risk factors, and cardiovascular risk profile -- 9 To Treat or Not To Treat?.