Introduction and Overview.-Target Volume Delineation: Different Tumor Entities -- Brain Gliomas and Brain Metastases -- Base of the Skulls/Orbita -- Spinal Column/ Spinal Cord -- Head- and Neck-Tumors -- Lung Tumors -- Liver and Pancreas Tumors.-Gastrointestinal Tumor: Esophagus -- Stomach -- Colorectal Carcinoma -- Anal Carcinoma -- Sarcoma -- Lymphomas -- Prostate Cancer -- Gynecological Cancer -- Bladder -- Mamma.