Part I: Evolution and Development of Missions -- Medical Missions: A Short History from There to Here -- The Evolution of Surgical and Humanitarian Missions -- The Global Burden of Surgical Need -- Comparative Economics of Anesthesia Care and the Global Anesthesia Workforce -- Planning a Mission, Fundraising, and Building a Team: The Kybele Experience -- Organizing and Developing Universal Anesthetic Equipment -- Materials Management -- What do Patients and Communities Expect of a Medical Mission? -- Anesthesia in Resource-Poor Settings: The Médecins sans Frontières Experience -- Quality Care: Maintaining Safety Through Minimum Standards -- Legal and Ethical Issues in Global Health: A Trip through the Vagaries of Truth and Culture -- Part II: Specific Case Related Implementation -- Strategies for Patient Assessment and Scheduling -- Postoperative Follow-up and Quality Maintenance -- Women's Rights and the Right to Pain Relief in Surgery and Labor -- Saving Sight In Developing Countries -- Cardiac Anaesthesthesia in Low Resource Settings -- Anesthesia Considerations for Facial Deformity Repair in Lesser Developed Countries -- Implementing a Regional Anesthesiology Service in a Low Resource Setting -- The Management of Pain in Less Developed Countries -- Living the Mission in Serbia and Other Less Affluent Worlds -- Anesthetic Management During the Lebanese Civil War -- Trauma, War, And Managing Vascular And Orthopedic Injuries -- Emergency Deployment in Disaster Areas -- Part III: Education at Home and Abroad -- Missions as a Part of  Medical Education and the Residency Curriculum -- Global Health Programs in Academic Centers.-  Closing the Professional Gap in Europe Through Education -- The Role of the Visiting Anesthesiologist in In-Country Education -- Letters (Lessons) from Around the World (Vignettes) -- The Future of Anesthesiology and Global Health in a Connected World.