section A. Introduction: H3 receptor target: past, present and future perspectives from worldwide H3 experts / Divya Vohora ... [et al.] ; Third histamine receptor : from discovery to clinics, long-lasting love story at INSERM and Bioprojet / Jean-Charles Schwartz ; Histamine as neurotransmitter / Oliver Selbach and Helmut L. Haas -- section B. The third histamine receptor: Phylogeny, gene structure, expression, and signaling / Pertti Panula ... [et al.] ; Drug discovery : from hits to clinical candidates / Sylvain Celanire, Florence Lebon, and Holger Stark ; Peripheral actions and therapeutic potential in periphery / Gabriella Coruzzi and Maristella Adami -- section C. Therapeutic potential in central nervous system disorders: Cognitive functions, attention-deficit hyperactivity disorders, and Alzheimer's disease / Maria-Beatrice Passani ... [et al.] ; Sleep disorders / Jonathan E. Shelton, Timothy W. Lovenberg, and Christine Dugovic ; Obesity / Timothy A. Esbenshade, Michael E. Brune, and Marina I. Strakhova ; Epilepsy / Divya Vohora and Krishna K. Pillai ; Schizophrenia / Kaitlin E. Browman ... [et al.] ; Other central nervous system diseases and disorders / Paul L. Chazot and Fiona C. Shenton.