chapter 1 Historical Perspective and Basics of Molecular Biology -- chapter 2 Systems and Technology Involving Bacteria -- chapter 3 Recombinant DNA Technology Using Mammalian Cells -- chapter 4 Biomimetic Systems -- chapter 5 Diffusional Processes and Engineering Design -- chapter 6 Microvascular Heat Transfer -- chapter 7 Perfusion Effects and Hydrodynamics -- chapter 8 Animal Surrogate Systems / chapter 9 Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease -- chapter 10 Control of the Microenvironment -- chapter 11 Interstitial Transport in the Brain: Principles for Local Drug Delivery -- chapter 12 Tools for Genome Analysis -- chapter 13 Vaccine Production -- chapter 14 Protein Engineering -- chapter 15 Metabolic Engineering -- chapter 16 Monoclonal Antibodies and Their Engineered Fragments -- chapter 17 Biomolecular Engineering in Oligonucleotide Applications -- chapter 18 Gene Therapy -- chapter 19 Bio-Nanorobotics: State of the Art and Future Challenges / chapter 20 DNA as a Scaffold for Nano-Structure Assembly -- chapter 21 Directed Evolution of Proteins for Device Applications / chapter 22 Semiconductor Quantum Dots for Molecular and Cellular Imaging -- chapter 23 Bionanotechnology for Bioanalysis -- chapter 24 Nano-Hydroxyapatite for Biomedical Applications -- chapter 25 Nanotechnology Provides New Tools for Biomedical Optics / chapter 26 Nanomaterials Perspectives and Possibilities in Nanomedicine / chapter 27 Biomedical Nanoengineering for Nanomedicine -- chapter 28 Physiogenomics: Integrating Systems Engineering and Nanotechnology for Personalized Medicine / chapter 29 Bionanotechnology Patenting: Challenges and Opportunities -- chapter 30 Fundamentals of Stem Cell Tissue Engineering -- chapter 31 Growth Factors and Morphogens: Signals for Tissue Engineering -- chapter 32 Extracellular Matrix: Structure, Function, and Applications to Tissue Engineering / chapter 33 Mechanical Forces on Cells -- chapter 34 Cell Adhesion -- chapter 35 Cell Migration -- chapter 36 Inflammatory and Immune Responses to Tissue Engineered Devices -- chapter 37 Polymeric Scaffolds for Tissue Engineering Applications -- chapter 38 Calcium Phosphate Ceramics for Bone Tissue Engineering -- chapter 39 Biomimetic Materials -- chapter 40 Nanocomposite Scaffolds for Tissue Engineering / chapter 41 Roles of Thermodynamic State and Molecular Mobility in Biopreservation -- chapter 42 Drug Delivery -- chapter 43 Gene Therapy -- chapter 44 Tissue Engineering Bioreactors / chapter 45 Animal Models for Evaluation of Tissue-Engineered Orthopedic Implants -- chapter 46 The Regulation of Engineered Tissues: Emerging Approaches -- chapter 47 Bioengineering of Human Skin Substitutes -- chapter 48 Nerve Regeneration: Tissue Engineering Strategies / chapter 49 Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration and Repair / chapter 50 Tissue Engineering Applications — Bone -- chapter 51 Cartilage Tissue Engineering -- chapter 52 Tissue Engineering of the Temporomandibular Joint -- chapter 53 Engineering Smooth Muscle -- chapter 54 Esophagus: A Tissue Engineering Challenge / chapter 55 Tissue Engineered Vascular Grafts -- chapter 56 Cardiac Tissue Engineering: Matching Native Architecture and Function to Develop Safe and Efficient Therapy -- chapter 57 Tissue Engineering of Heart Valves -- chapter 58 Tissue Engineering, Stem Cells and Cloning for the Regeneration of Urologic Organs -- chapter 59 Hepatic Tissue Engineering for Adjunct and Temporary Liver Support -- chapter 60 Tissue Engineering of Renal Replacement Therapy -- chapter 61 The Bioengineering of Dental Tissues -- chapter 62 Tracheal Tissue Engineering -- chapter 63 Artificial Heart and Circulatory Assist Devices -- chapter 64 Cardiac Valve Prostheses -- chapter 65 Vascular Grafts -- chapter 66 Artificial Lungs and Blood–Gas Exchange Devices -- chapter 67 Artificial Kidney -- chapter 68 Peritoneal Dialysis Equipment -- chapter 69 Therapeutic Apheresis and Blood Fractionation -- chapter 70 Liver Support Systems -- chapter 71 Artificial Pancreas / chapter 72 Nerve Guidance Channels -- chapter 73 Tracheal, Laryngeal, and Esophageal Replacement Devices -- chapter 74 Artificial Blood -- chapter 75 Artificial Skin and Dermal Equivalents -- chapter 76 Beneficence, Nonmaleficence, and Medical Technology -- chapter 77 Ethical Issues Related to Clinical Research.