Introduction and Fundamentals of Optimized Adaptive Controllers and Systems -- Introduction to Optimized Adaptive Controllers and Systems -- Scenarios, Notation and Stability Conditions -- Exercises for Part I -- Design of the Driver Block: Basic and Extended Predictive Control Strategies -- Basic Strategy of Predictive Control -- Extended Strategy of Predictive Control -- Exercises for Part II -- Design of the Adaptation Mechanism: Synthesis of the Adaptive System -- Analysis and Synthesis of the Adaptive System in the Real Case -- Exercises for Part III -- Stability Theory of Adaptive Predictive Control -- Stability Theory -- Exercises for Part IV -- Benchmark Applications of Predictive, Adaptive Predictive, and Optimized Adaptive Control -- Multivariable Control of a Distillation Column -- Control of a Bleach Plant in a Pulp Factory -- Technological realization of ADEX Optimized Adaptive Control Systems -- A Software Platform for Adaptive Predictive Expert Control Applications -- Application of ADEX COP v.1 to the Biological Process of a Wastewater Treatment Plant -- ADEX Optimized Adaptive Control System for the Sulfur Recovery Process at Pemex Cadereyta Refinery -- ADEX Optimized Adaptive Control System for Superheated Steam Temperature in a Coal-Fired Power Plant -- Appendices: Some Basic Concepts of System Analysis; Other Predictive Models and Performance Indices; Input/Output Properties of Stable Linear Processes; ADEX COP Manuals.