chapter 1 Rationale for early screening for diabetic renal disease / chapter 2 PRESSURE-INDUCED AND METABOLIC ALTERATIONS IN THE GLOMERULUS: CYTOSKELETAL CHANGES / chapter 3 THE STENO HYPOTHESIS FOR CARDIOVASCULAR AND RENAL DISEASE REVISITED / chapter 4 MICROALBUMINURIA AND CARDIOVASCULAR DISEASE / chapter 5 The heart in diabetes: results of trials Giulio Zuanetti and Elena Sarugeri -- chapter 6 MICROALBUMINURIA AND GFR IN TYPE 1 AND TYPE 2 DIABETES / chapter 7 SERUM CREATININE AND OTHER MEASURES OF GFR IN DIABETES / chapter 8 FAMILIAL FACTORS IN DIABETIC NEPHROPATHY / chapter 9 GENETICS AND DIABETIC NEPHROPATHY / chapter 10 LOW BIRTH WEIGHT AND DIABETIC NEPHROPATHY / chapter 11 EFFECTS OF INSULIN ON THE CARDIOVASCULAR SYSTEM AND THE KIDNEY / chapter 12 Value of screening for microalbuminuria in people with diabetes as well as in the general population / chapter 13 DYSFUNCTION OF THE VASCULAR ENDOTHELIUM AND THE DEVELOPMENT OF RENAL AND VASCULAR COMPLICATIONS IN DIABETES / chapter 14 PATHOGENESIS AND MANAGEMENT OF BACTERIAL URINARY TRACT INFECTIONS IN ADULT PATIENTS WITH DIABETES MELLITUS / chapter 15 PATHOLOGY OF THE KIDNEY IN DIABETES MELLITUS / chapter 16 RENAL STRUCTURAL CHANGES IN PATIENTS WITH TYPE 1 DIABETES AND MICROALBUMINURIA / chapter 17 RENAL STRUCTURE IN TYPE 2 DIABETES / chapter 18 NEPHROPATHY IN TYPE 2 DIABETIC PATIENTS, PREDICTORS OF OUTCOME / chapter 19 ADVANCED GLYCATION END-PRODUCTS AND DIABETIC RENAL DISEASE / chapter 20 PROTEIN KINASE C ACTIVATION AND ITS INHIBITION FOR THE TREATMENT OF DIABETIC RENAL PATHOLOGIES / chapter 21 BIOCHEMICAL ASPECTS OF DIABETIC NEPHROPATHY / chapter 22 PATHOGENESIS OF DIABETIC GLOMERULOPATHY: THE ROLE OF GLOMERULAR HEMODYNAMIC FACTORS / chapter 23 The emerging role of growth factor hormone (GH) and vascular endothelial growth factor (VEGF) in diabetic kidney disease / chapter 24 TRANSFORMING GROWTH FACTOR- AND OTHER CYTOKINES IN EXPERIMENTAL AND HUMAN DIABETIC NEPHROPATHY / chapter 25 BLOOD PRESSURE ELEVATION IN DIABETES: THE RESULTS FROM 24-h AMBULATORY BLOOD PRESSURE RECORDINGS / chapter 26 MICROALBUMINURIA IN YOUNG PATIENTS WITH TYPE 1 DIABETES / chapter 27 EARLY RENAL HYPERFUNCTION AND HYPERTROPHY IN IDDM, INCLUDING COMMENTS ON EARLY INTERVENTION / chapter 28 AUTOREGULATION OF GLOMERULAR FILTRATION RATE IN PATIENTS WITH DIABETES / chapter 29 The role of renal biopsy in the clinic Satishkumar A Jayawardene and Neil S. Sheering -- chapter 30 INHIBITION OF THE RENIN ANGIOTENSIN ALDOSTERONE SYSTEM, WITH PARTICULAR REFERENCE TO THE DUAL BLOCKADE PRINCIPLE / chapter 31 THE CONCEPT OF INCIPIENT DIABETIC NEPHROPATHY AND THE EFFECT OF EARLY ANTIHYPERTENSIVE INTERVENTION / chapter 32 THE ROLE OF PROTEINURIA IN THE DIAGNOSIS AND TREATMENT OF TYPE 2 DIABETES / chapter 33 ANTIHYPERTENSIVE TREATMENT IN TYPE 2 DIABETES, WITH SPECIAL REFERENCE TO ABNORMAL ALBUMINURIA: A FOCUS ON THE NEW TRIALS / chapter 34 BLOOD PRESSURE LOWERING TREATMENT AND THE PREVENTION OF STROKE IN THE DIABETIC PATIENT / chapter 35 NON-GLYCAEMIC INTERVENTION IN DIABETIC NEPHROPATHY: THE ROLE OF DIETARY PROTEIN AND SALT INTAKE / chapter 36 DIABETIC NEPHROPATHY AND PREGNANCY / chapter 37 EVOLUTION WORLDWIDE OF RENAL REPLACEMENT THERAPY IN DIABETES / chapter 38 HEMODIALYSIS AND CAPD IN TYPE 1 AND TYPE 2 DIABETIC PATIENTS WITH ENDSTAGE RENAL FAILURE / chapter 39 Renal and pancreas transplants in diabetes / chapter 40 COMBINATION THERAPY FOR HYPERTENSION AND RENAL DISEASE IN DIABETES / chapter 41 MICROALBUMINURIA IN ESSENTIAL HYPERTENSION: CARDIOVASCULAR AND RENAL IMPLICATIONS / chapter 42 A COMPARISON OF PROGRESSION IN DIABETIC AND NON-DIABETIC RENAL DISEASE: SIMILARITY OF PROGRESSION PROMOTERS / chapter 43 SCIENTIFIC BASIS FOR NEW GUIDELINES FOR THE TREATMENT OF HYPERTENSION IN TYPE 2 DIABETES / chapter 44 REGULATORY CONSIDERATIONS IN THE DEVELOPMENT OF THERAPIES FOR DIABETIC NEPHROPATHY AND RELATED CONDITIONS / chapter 45 Diabetes, hypertension, and kidney disease in the Pima Indians / chapter 46 THE DEVELOPMENT AND PROGRESSION OF CLINICAL NEPHROPATHY IN WHITE PATIENTS WITH TYPE 2 DIABETES / chapter 47 MICROALBUMINURIA, BLOOD PRESSURE AND DIABETIC RENAL DISEASE: ORIGIN AND DEVELOPMENT OF IDEAS