1. Historical aspects of narcolepsy / William C. Dement -- 2. English translations of the first clinical reports on barcolepsy by Gelineau and on cataplexy by Westphal in the Late 19th Century, with commentary / Carlos H. Schenck. [et al.] -- 3. Historical aspects of the treatment for narcolepsy / Yasuo Hishikawa and Tetsuo Shimizu -- 4. Narcolepsy and hypersomnia : immunogenetic aspects of narcolepsy--past, present, and future / Yutaka Honda, Minae Kawashima, and Katsushi Tokunaga -- 5. The hypocretins : discovery and emerging role as integrators of physiological signals / Luis de Lecea. [et al.] -- 6. Cataplexy / Christian Guilleminault, Ji Hyun Lee, and Viola Arias -- 7. Effect of age on narcolepsy / Yves Dauvilliers, Jacques Montplaisir, and Michel Billiard -- 8. Narcolepsy in children and adolescents / Sona Nevsimalova -- 9. Idiopathic hypersomnia / Michel Billiard and Yves Dauvilliers -- 10. Kleine-Levin syndrome and other recurrent hypersomnias / Claudio Bassetti. [et al.] -- 11. Spectrum of narcolepsy / Claudio L. Bassetti -- 12. Sleep paralysis, state transition disruptions, and narcolepsy / James Allan Cheyne -- 13. Epidemiology of narcolepsy : development of the Ullanlinna Narcolepsy Scale / Christer Hublin -- 14. Epidemiology of narcolepsy / Maurice M. Ohayon -- 15. Automatic behavior, sleep paralysis, hypnagogic hallucinations, cataplexy : narcolepsy spectrum and alternate etiologies / Mariana Szklo-Coxe. [et al.] -- 16. Neurophysiology of cataplexy and cataplexy-like phenomena / Sebastiaan Overeem. [et al.] --

17. Abnormal motor activity during sleep in narcolepsy / Jacques Montplaisir. [et al.] -- 18. Circadian and ultradian aspects in narcolepsy / Franco Ferrillo and Lino Nobili -- 19. Homeostatic sleep regulation in narcolepsy / Ramin Khatami. [et al.] -- 20. Daytime variations in alertness/drowsiness and vigilance in narcolepsy/cataplexy / Roger J. Broughton -- 21. Molecular characterization of hypocretin/orexin and melanin concentrating hormone neurons : relevance to narcolepsy / Christelle Peyron -- 22. Nocturnal polysomnography, multiple sleep latency test and maintenance of wakefulness test in narcolepsy / Merrill M. Mitler -- 23. Canine narcolepsy : history and pathophysiology / Emmanuel Mignot -- 24.Vigilance tests in narcolepsy / Johannes Mathis and Christian W. Hess -- 25. Lessons from sleepy mice : narcolepsy-cataplexy and the orexin neuropeptide system / Jon T. Willie and Masashi Yanagisawa -- 26. Hypocretin-1 studies in cerebrospinal fluid : european experience / Christian R. Baumann. [et al.] -- 27. CSF hypocretin-1/orexin-A in narcolepsy : technical aspects and clinical experience in the United States / Emmanuel Mignot -- 28. Hypocretin pathology in human narcolepsy / Thomas C. Thannickal and Jerome M. Siegel -- 29. Symptomatic narcolepsy with cataplexy and without cataplexy or hypersomnia, with and without hypocretin (orexin) deficiency / T. Kanbayashi. [et al.] --

30. Poststroke and posttraumatic hypersomnia / Claudio L. Bassetti and Christian R. Baumann -- 31. Potential mechanisms of the wake-promoting action of hypocretin/orexin / Michael Muhlethaler -- 32. Normal role of hypocretin/orexin / Jerome M. Siegel -- 33. Role of hypocretin/orexin in the neurobiology of sleep and alertness / Jamie M. Zeitzer and Emmanuel Mignot -- 34. Hypocretin, GABA[subscript B] receptors and sleep / Thomas S. Kilduff. [et al.] -- 35. The Activity profile of hypocretin neurons in the freely moving rat / Boris Y. Mileykovskiy, Lyudmila I. Kiyashchenko, and Jerome M. Siegel -- 36. Input and output of orexin/hypocretin neurons : link between arousal pathways and feeding behavior / Takeshi Sakurai -- 37. Human leukocyte antigen and narcolepsy : present status and relationship with familial hstory and hypocretin deficiency / Ling Lin and Emmanuel Mignot -- 38. Non-HLA genes in narcolepsy / Mehdi Tafti -- 39. Mutation screening of the hypocretin system genes in narcolepsy / Juliette Faraco and Emmanuel Mignot -- 40. Environmental factors in narcolepsy / Michel Billiard and Cecilia Orellana -- 41. Autoimmune studies in narcolepsy / Michael H. Silber. [et al.] -- 42. Metabolic abnormalities in human narcolepsy / Thomas Pollmacher, Pierre Beitinger, and Andreas Schuld -- 43. Hormonal abnormalities in hypocretin/orexin deficient human narcolepsy / Gert Jan Lammers, Sebastiaan Overeem, and Hanno Pijl -- 44. Psychosocial impact of narcolepsy / Adrian M. Siegel and Roger J. Broughton -- 45. Narcolepsy and driving / Jean Krieger and Christine Erhardt -- 46. Comorbidity in narcolepsy / Geert Mayer, Thomas Penzel, and Karl Kesper --

47. The behavioral management of narcolepsy / Roger J. Broughton and Brian J. Murray -- 48. Pharmacology of CNS stimulants / Seiji Nishino and Emmanuel Mignot -- 49. Anticataplectic Medications / Seiji Nishino -- 50. Modafinil : mechanisms of action / Thomas E. Scammell -- 51. Modafinil : the european experience / Michel Billiard. [et al.] -- 52. Modafinil : the U.S. experience / Michael Thorpy -- 53. Molecular and cellular actions of [gamma]-hydroxybutyric acid : possible mechanisms underlying GHB efficacy in narcolepsy / Xinmin S. Xie, Daniel Pardi, and Jed Black -- 54. Sodium oxybate for the treatment of narcolepsy / Jed Black -- 55. Perspectives for new treatments : an update / Emmanuel Mignot and Seiji Nishino -- 56. Diagnostic criteria for syndromes of excessive daytime sleepiness / Emmanuel Mignot, Michel Billiard, and Claudio L. Bassetti.