1. Introduction / S.G.O. Johansson -- 2. Serum IgE distributions in normal and asthmatic subjects / Chantal Matkin Dolan. [et al.] -- 3. Understanding the binding of IgE to its high-affinity receptor and to an anti-IgE antibody / Leonard G. Presta and Robert L. Shields -- 4. Mediator release from basophils and mast cells and its relationship to FceRI expression and IgE-suppressing therapies / Donald W. MacGlashan. [et al.] -- 5. Expression of IgE receptors on eosinophils / David Dombrowicz, Andre Capron, and Monique Capron -- 6. Eosinophil IgE receptors : controversy and consensus / Hirohito Kita and Cheryl R. Adolphson -- 7. Murine models of asthma : caveats and conclusions on the contribution of IgE and mast cells to allergic inflammation, airway hyperresponsiveness, and airflow obstruction / Jeffrey S. Tepper and Daniel B. Tumas -- 8. Role of IgE in asthma : pathogenesis and novel therapeutic strategies / James Laurence Lordan, Stephen T. Holgate, and Ian Sayers -- 9. IgE-mediated response to allergen in the bronchoprovocation laboratory / Louis-Philippe Boulet and Donald W. Cockcroft -- 10. Pathophysiology of the airway response to inhaled allergen in asthmatic subjects : role of IgE / John V. Fahy -- 11. Efficacy and safety of xolair anti-IgE monoclonal antibody in adult asthmatics / Robert B. Fick, Jr., and W. James Metzger -- 12. The role of IgE in pediatric asthma / Henry Milgrom and Charles Johnson -- 13. Anti-inflammatory activities of omalizumab (xolair), a recombinant humanized monoclonal antibody binding IgE / Robert B. Fick, Jr. -- 14. Pulmonary delivery of anti-IgE : rationale for topical delivery to the airway / Theresa D. Sweeney. [et al.] -- 15. Treatment of seasonal allergic rhinitis / Thomas B. Casale and Patricia W. Rohane -- 16. Anti-IgE and allergic skin diseases / Michael F. Hofer and Donald Y.M. Leung -- 17. Role of IgE and food allergens / Ricki M. Helm and A. Wesley Burks -- 18. Role of IgE in allergic bronchopulmonary aspergillosis / Priscilla S.A. Sarinas and Rajinder K. Chitkara -- 19. IgE and its role in parasitic helminth infection : implications for anti-IgE-based therapies / Philip J. Cooper and Thomas B. Nutman -- 20. The rise of antibodies as therapeutics / Maureen P. Quan and Paul Carter.