1. Dimensional analysis and scale-up in theory and industrial application / Marko Zlokarnik -- 2. Engineering approaches for pharmaceutical process scale-up, validation, optimization, and control in the PAT era / Fernando J. Muzzio -- 3. Understanding scale-up and quality risks on the interface between primary and secondary development / Frans L. Muller [and others] -- 4. Scale-up and process validation / Steven Ostrove -- 5. Parenteral drug scale-up / Igor Gorsky -- 6. Nonparenteral liquids and semisolids / Lawrence H. Block -- 7. Scale-up considerations for biotechnology-derived products / Marco Cacciuttolo, John Chon, and Greg Zarbis-Papastoitsis -- 8. Powder handling / James K. Prescott -- 9.1. Batch size increase in dry blending and mixing / Albert W. Alexander and Fernando J. Muzzio -- 9.2. Scale-up of continuous blending / Aditya U. Vanarase [and others] -- 10. Scale-up in the field of granulation and drying / Hans Leuenberger [and others] -- 11. Batch size increase in fluid bed granulation / Dilip M. Parikh -- 12. Roller compaction scale-up / Ronald W. Miller -- 13. Scale-up of extrusion and spheronization / Raman M. Iyer, Harpreet K. Sandhu, and Navnit H. Shah -- 14.1. Scale-up of compaction and the tableting process / Matthew P. Mullarney and Jeffrey Moriarty -- 14.2. Dimensional analysis of the tableting process / Michael Levin and Marko Zlokarnik -- 15. Practical considerations in the scale-up of powder-filled hard shell capsule formulations / Larry L. Augsburger -- 16. Scale-up of film coating / Stuart C. Porter -- 17. Virtual scale-up of manufacturing solid dosage forms / Hans Leuenberger, Michael N. Leuenberger, and Maxim Puchkov.