part Part I General Considerations -- chapter 1 Risk Assessment of Marine Toxins / chapter 2 Analysis of Marine Toxins—Techniques, Method Validation, Calibration Standards, and Screening Methods -- part Part II The Epidemiological Impact of Toxic Episodes -- chapter 3 Epidemiological Impact of Diarrheic Toxins / chapter 4 Epidemiologic Impact of Toxic Episodes: Neurotoxic Toxins / part Part III Diversity of Marine Toxins as Pharmacological Tools -- chapter 5 Calcium Channels for Exocytosis: Functional Modulation with Toxins / chapter 6 The Mouse Bioassay as a Universal Detector / part Part IV Paralytic Shellfish Poisoning (PSP) -- chapter 7 Metabolism of Paralytic Shellfish Toxins Incorporated into Bivalves / chapter 8 Chemical Analysis / chapter 9 Paralytic Shellfish Toxins—Pharmacology, and Toxicology Biological Detection Methods -- part Part V Diarrheic Episodes: Phosphatase Inhibitors -- chapter 10 Chemistry, Metabolism, and Chemical Analysis of Okadaic Acid Group Toxins -- chapter 11 Pharmacology and Toxicology of Diarrheic Shellfish Toxins / part Part VI Lipophyllic Toxins: Nonphosphatase Inhibitors -- chapter 12 Planktonic Dinoflagellates That Contain Polyether Toxins of the Old “DSP Complex” -- part Part VIA Yessotoxins -- chapter 13 Chemistry, Metabolism, and Chemical Analysis / chapter 14 Pharmacology and Mechanism of Action: Biological Detection / chapter 15 Toxicology of the Yessotoxins / part Part VIB Pectenotoxins -- chapter 16 Chemistry, Metabolism, and Chemical Detection Methods of Pectenotoxins -- chapter 17 Pharmacology of Pectenotoxins / chapter 18 Toxicology of the Pectenotoxins / part Part VII Domoic Acid Intoxication -- chapter 19 Ecobiology of Amnesic Shellfish Toxin Producing Diatoms / chapter 20 Domoic Acid: Detection Methods, Pharmacology, and Toxicology / part Part VIII Non-PSP Neurotoxic Episodes -- chapter 21 Ecobiology of the Brevetoxin, Ciguatoxin, and Cyclic Imine Producers -- part Part VIIIA Ciguatera Toxins -- chapter 22 Ciguatera Toxins: Chemistry, Toxicology, and Detection / part Part VIIIB Maitotoxin -- chapter 23 Maitotoxin: A Unique Pharmacological Tool for Elucidating Ca2+-Dependent Mechanisms -- part Part VIIIC Brevetoxins -- chapter 24 The Molecular and Integrative Basis to Brevetoxin Toxicity / chapter 25 Detection of Brevetoxins in the Twenty-First Century / part Part VIIID Cyclic Imines -- chapter 26 Cyclic Imine Toxins: Chemistry, Biogeography, Biosynthesis, and Pharmacology -- chapter 27 Toxicology of Cyclic Imines: Gymnodimine, Spirolides, Pinnatoxins, Pteriatoxins, Prorocentrolide, Spiro-Prorocentrimine, and Symbioimines -- part Part VIIIE Polycavernosides and Gambierol -- chapter 28 Polycavernosides and Gambierol: Chemistry, Pharmacology, Toxicology, and Detection -- part Part IX Palytoxin, Ostreocin, Ovatatoxin -- chapter 29 Palytoxin and Analogues: Ecobiology and Origin, Chemistry, Metabolism, and Chemical Analysis -- chapter 30 Diverse Chemical Structures and Bioactivities of Marine Toxin: Palytoxin and Symbiodinolide -- chapter 31 Palytoxins: Pharmacology and Biological Detection Methods / chapter 32 Occurrence and Toxicology of Palytoxins / part Part X Pfiesteria Toxins -- chapter 33 A Decade of Research on Pfiesteria Spp. and Their Toxins: Unresolved Questions and an Alternative Hypothesis -- part Part XI Azaspiracids -- chapter 34 Pharmacology and Epidemiological Impact of Azaspiracids / chapter 35 Azaspiracids: Chemistry, Bioconversion, and Determination / chapter 36 Toxicology of Azaspiracid-1: Acute and Chronic Poisoning, Tumorigenicity, and Chemical Structure Relationship to Toxicity in a Mouse Model -- part Part XII Cyanobacterial Toxins -- chapter 37 Cyanobacterial Toxins in Aquaculture / part Part XIIA Neurotoxins -- chapter 38 Cyanobacterial Neurotoxins, Anatoxin-A and Analogues: Detection and Analysis -- part Part XIIB Hepatotoxins -- chapter 39 Cyanobacterial Hepatotoxins: Chemistry, Biosynthesis, and Occurrence / chapter 40 Hepatotoxins: Context and Chemical Determination / part Part XIII Toxins as a Starting Point to Drugs -- chapter 41 Marine Neurotoxins as a Starting Point to Drugs / part Part XIV Legal and Economic Views -- chapter 42 Incidence of Marine Toxins on Industrial Activity / chapter 43 Toxin Monitoring Programs and Regulatory View