chapter 1 Meta-analysis: Past and Present Challenges / chapter 2 Meta-analysis of Heterogeneously Reported Study Results: A Bayesian Approach -- chapter 3 Meta-analysis versus Large Trials: Resolving the Controversy / chapter 4 A Bayesian Meta-analysis of Randomized Mega-trials for the Choice of Thrombolytic Agents in Acute Myocardial Infarction -- chapter 5 Combining Studies with Continuous and Dichotomous Responses: A Latent- Variables Approach -- chapter 6 Computer-modeling and Graphical Strategies for Meta-Analysis / chapter 7 Meta-analysis for 2-2 Tables with Multiple Treatment Groups / chapter 8 A Bayesian Meta-analysis of the Relationship between Duration of Estrogen Exposure and Occurrence of Endometrial Cancer -- chapter 9 Modeling and Implementation Issues in Bayesian Meta-Analysis / chapter 10 Meta-analysis of Population Pharmacokinetic Data / chapter 11 Meta-analysis of Individual-patient Survival Data Using Random-effect Models -- chapter 12 Adjustment for Publication Bias and Quality Bias in Bayesian Meta-analysis / chapter 13 Meta-analysis of Clinical Trials: Opportunities and Limitations / chapter 14 Research Synthesis for Public Health Policy: Experience of the Institute of Medicine -- chapter 15 Meta-analysis in Practice: A Critical Review of Available Software.